How to Choose Cleanroom Wall Panels? A Complete Comparison of 5 Common Materials

When it comes to constructing or upgrading a cleanroom, one of the most critical decisions lies in choosing the right cleanroom wall panels. These panels not only influence cleanliness and contamination control but also affect long-term durability, maintenance cost, and compliance with industry standards.

In this article, we break down five of the most common materials used in cleanroom wall panels and help you evaluate their pros and cons—so you can make a smarter investment.

1. Stainless Steel Panels: Durable but Costly

If hygiene, corrosion resistance, and strength top your list, stainless steel wall panels are hard to beat. Their smooth surfaces make them easy to clean, and they are highly resistant to both impact and harsh chemicals—ideal for pharmaceutical and high-sterility environments.

However, their higher cost and weight can increase installation complexity and overall project expenses. If your cleanroom does not demand extreme durability, alternative materials may offer better cost-efficiency.

2. Aluminum Honeycomb Panels: Lightweight and Strong

Aluminum honeycomb panels are a popular choice due to their lightweight structure and high mechanical strength. The honeycomb core ensures dimensional stability and excellent fire resistance, while the aluminum surface resists oxidation.

One downside is that these panels can be dented more easily than steel, especially in high-traffic areas. They are best suited for cleanrooms that require frequent modifications or panel relocations.

3. HPL (High-Pressure Laminate) Panels: Budget-Friendly and Easy to Install

HPL cleanroom wall panels are known for their affordability and ease of installation. Their laminated surface provides good resistance to scratches, abrasion, and moisture, making them suitable for environments with moderate cleanroom classification.

However, they are not ideal for high-humidity or chemical-intensive areas, as prolonged exposure can compromise surface integrity.

4. PVC-Coated Panels: Chemical Resistant but Prone to Damage

PVC-coated wall panels offer excellent chemical resistance, making them a go-to option for laboratories and certain electronic manufacturing areas. They are also cost-effective and available in various thicknesses.

The main trade-off? PVC coatings can scratch or delaminate over time, especially in environments with physical contact or cleaning equipment. Careful handling and proper installation are crucial for maximizing lifespan.

5. Magnesium Oxide (MgO) Panels: Fireproof and Eco-Friendly

MgO panels are gaining popularity thanks to their non-combustibility, moisture resistance, and environmental friendliness. They are ideal for projects seeking green building certifications and enhanced fire safety.

However, these panels can be more brittle than others and may require reinforcement in structural applications. Also, make sure to source high-quality MgO panels to avoid performance inconsistencies.

Choose What Matches Your Cleanroom’s Needs

Selecting the right cleanroom wall panels isn’t just about price—it’s about functionality, durability, and long-term compliance. Consider factors like chemical exposure, humidity, fire safety, and ease of maintenance before making a decision.

For cleanrooms that demand high sterility, stainless steel or aluminum may be ideal. For cost-sensitive applications, HPL or PVC-coated panels could be a better fit. For sustainability-focused projects, MgO panels offer a smart choice.

Ready to upgrade your cleanroom with the right wall panel solution? Contact Best Leader today and let our cleanroom experts help you make the right choice.